Iraqi Journal of Veterinary Sciences

Abstract

The contemporary reading was deliberated to explore the valuable responsibility of propolis, a biologically brisk flavonoid, in opposition to methotrexate- (MTX-) caused hurt of the liver and kidney in chicks. Chicks customary a multiple intraperitoneal gaves of MTX (40 mg/kg) moreover unaided or in mixture with verbal propolis (100 mg/kg). Serum was second-hand to gauge tissue hurt scores, although the hepatic and renal tissue sections were taken for point histopathological inspection. Propolis cure rearranges the MTX-caused altitude of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, creatinine, alkaline phosphatase (AP), and uric acid; additionally, propolis doses ameliorated MTX effects contrast to the MTX-intoxicated cluster. Histopathological inspection confirms that propolis notably lessens the MTX-caused histological variation and practically renew the typical style of hepatic and renal. In conclusion, propolis may be a hopeful driving force for the guard in opposition to MTX-caused cytotoxicity in chicks. Histopathological inspection confirms that propolis notably lessens the MTX-caused histological variation and practically renew the typical style of hepatic and renal. In conclusion, propolis may be a hopeful driving force for the guard in opposition to MTX-caused cytotoxicity in chicks.