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Iraqi Journal of Veterinary Sciences

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Protective effect of propolis on liver and kidney injury caused by methotrexate in chicks

    Saevan S. Saad Al-Mahmood Maab A. Fadel

Iraqi Journal of Veterinary Sciences, In Press
10.33899/ijvs.2022.133021.2162

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Abstract

The contemporary reading was deliberated to explore the valuable responsibility of propolis, a biologically brisk flavonoid, in opposition to methotrexate- (MTX-) caused hurt of the liver and kidney in chicks. Chicks customary a multiple intraperitoneal gaves of MTX (40 mg/kg) moreover unaided or in mixture with verbal propolis (100 mg/kg). Serum was second-hand to gauge tissue hurt scores, although the hepatic and renal tissue sections were taken for point histopathological inspection. Propolis cure rearranges the MTX-caused altitude of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, creatinine, alkaline phosphatase (AP), and uric acid; additionally, propolis doses ameliorated MTX effects contrast to the MTX-intoxicated cluster. Histopathological inspection confirms that propolis notably lessens the MTX-caused histological variation and practically renew the typical style of hepatic and renal. In conclusion, propolis may be a hopeful driving force for the guard in opposition to MTX-caused cytotoxicity in chicks. Histopathological inspection confirms that propolis notably lessens the MTX-caused histological variation and practically renew the typical style of hepatic and renal. In conclusion, propolis may be a hopeful driving force for the guard in opposition to MTX-caused cytotoxicity in chicks.
Keywords:
    methotrexate,, ,،,؛propolis,, ,،,؛bee glue
Main Subjects:
  • Veterinary Pharmacology and Toxicology
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(2022). Protective effect of propolis on liver and kidney injury caused by methotrexate in chicks. Iraqi Journal of Veterinary Sciences, (), -. doi: 10.33899/ijvs.2022.133021.2162
Saevan S. Saad Al-Mahmood; Maab A. Fadel. "Protective effect of propolis on liver and kidney injury caused by methotrexate in chicks". Iraqi Journal of Veterinary Sciences, , , 2022, -. doi: 10.33899/ijvs.2022.133021.2162
(2022). 'Protective effect of propolis on liver and kidney injury caused by methotrexate in chicks', Iraqi Journal of Veterinary Sciences, (), pp. -. doi: 10.33899/ijvs.2022.133021.2162
Protective effect of propolis on liver and kidney injury caused by methotrexate in chicks. Iraqi Journal of Veterinary Sciences, 2022; (): -. doi: 10.33899/ijvs.2022.133021.2162
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