Antimicrobial activity of peptides extracted from camels' blood neutrophils against some pathogenic bacteria
The aim of this search was to isolate and purify Antimicrobial cationic peptides (AMPs) taken from camel blood , and to study its antibacterial activity against some multidrug resistant pathogenic bacteria (Salmonella typhimurium , Bacillus subtilis) .
The results showed the possibility of obtaining these peptides from camel's white blood cells , and was separated by using Reversed-Phased High Performance Liquid Chromatography (RP-HPLC) technical equipment. The results showed the presence of (21) absorption peaks of the isolated peptide extract .
The two-stage radial diffusions method was used to study the activity of the crude peptide against the studied bacteria (Salmonella typhimurium , Bacillus subtilis) . The results showed that this peptides was effective without any resistance. the best effect was on the gram positive bacteria (Bacillus subtilis) with a diameter of (31mm) inhibition, while the less effect was on the negative bacteria (Salmonella typhimurium) with a diameter of (20mm) .
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