1 Department of Pathology, College of Veterinary Medicine, University of Mosul, Mosul, Iraq

2 Department of Pathology and Poultry Diseases, College of Veterinary Medicine, University of Mosul, Mosul, Iraq


Coronaviruses (CoVs) are important RNA viruses that affect respiratory, gastrointestinal and urinary system of human being and birds. These viruses originated from the subfamily Coronavirinae which genetically includes Alphacoronavirus, Beta coronavirus, Gamma coronavirus and Delta coronavirus. The sequencing analysis of the genome showed that COVID-19 caused by SARS-CoV-2 belongs to Beta coronavirus genus and avian infectious bronchitis caused by IBV comes from Gamma coronavirus genus. Over the past few decades and until now, the world showed that endemic outbreaks of infectious bronchitis in avian caused by IBV. Once more, the world sees the emergence of another new human coronavirus COVID-19 outbreak due to a new strain called SARS-CoV-2. Whole genetic material and comparative genomic analysis exhibited that IBV and SARS-CoV-2 have particularly same genomic structures and characteristics. Both have a spike protein in the genome structure which allows that SARS-CoV-2 attaches to their human select cells throughout ACE2 receptors, that are notably reported in the lung and kidney. While IBV uses alpha (2,3) linked sialic acids-dependent manner for bind to the avian tissues which is notably reported in the lung and kidney. The two diseases are produced a pulmonary and urinary infection that lead to sneezing, gasping, respiratory massive destruction, severe pneumonia and renal failure. This review will introduce a general overview of two diseases and describe the phylogeny, epidemiology, pathogenesis, clinical features, autopsy report and microscopic lesions.


  1. Now, the world is facing the proceed of COVID‐19 epidemic in human.
  2. Previously, the world also faced the progress of IBV epidemic in avian.
  3. The purpose of our review article is to give people a similarities and differences of COVID-19 and Avian Infectious Bronchitis.
  4. We review the latest published papers on COVID‐19 and Avian Infectious Bronchitis.
  5. In this paper, we review a general overview of two diseases and describe the phylogeny, epidemiology, pathogenesis, clinical features, autopsy report, microscopic lesions and insight on vaccine.


Main Subjects

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