Keywords : liver

Effects of Newcastle disease vaccine on the liver and antioxidant enzymes of chicks

N. G. Mustafa

Iraqi Journal of Veterinary Sciences, Volume 32, Issue 2, Pages 243-247
DOI: 10.33899/ijvs.2019.153856

Newcastle disease is a highly contagious disease of domestic and wild birds result in huge economic losses due to extreme morbidity and mortality. The aim of this paper is to explore the possibility of the harmful impact of Newcastle disease vaccine on certain biochemical profiles regarded to chicken liver. This study conducted during January-April 2014, one day old - 53 chicks were divided into two groups; vaccinated (with Newcastle disease vaccine) group at the age of 1, 3, and 7 days and unvaccinated group. Results show damaging effects of vaccination on the liver glycogen and malondialdehyde concentrations, serum superoxide dismutase, catalase, glutathione peroxidase, gamma-glutamyl transferase, alanine transaminase, and aspartate transaminase activities. In contrast, studied parameters look to return to their usual range at the age of 30 days. From the convincing outcome of our investigation, it can be concluded that Newcastle disease vaccination has a detrimental influence on the liver of chickens, nonetheless this effect can be overwhelmed by the time.

Comparative histopathological effects of aqueous, hexane extracts of Iraqi sweet almond (Prunus amygdalus) with atorvastatin for treating hyperlipidemia induced in mice

L.A. Kafi; N.TH.N. Al- Ezzi

Iraqi Journal of Veterinary Sciences, Volume 31, Issue 1, Pages 13-21
DOI: 10.33899/ijvs.2017.126705

This research was carried out to find out the treatment impact of aqueous and hexane extracts of sweet almond (Prunus amygdalus) on some histopathological indicators of heart, aorta and liver related to hyperlipidemia that induced in mice and compare them with Atorvastatin. Sweet almond was dried and grinded by an electrical grinder to form fine crude powder that extracted by two ways: by using 95% hexane and water by using the distilled water with Soxhlet apparatus. Forty mature mice were randomly divided into 8 groups (5 mice per group) and treated every day for 60 days, the first group was fed and drank normally and regarded as a negative control group, a second group was given polypropylene glycol offered as negative control group, third group was given tap water containing 0.5% of hydrogen peroxide and 1% of cholesterol in the feed for 60 days for induction of hyperlipidemia and offered as positive control group. Hyperlipidemia was induced in the other five groups as in the third group. The treatment of hyperlipidemia was done by using hexane extract at a dose of 500 mg/ kg of body weight and aqueous extract of sweet almond with three different doses (500, 750 and 1000) mg/ kg of body weight and compared with the other group that treated with atorvastatin 20 mg/ kg B.W. as antihyperlipidemic drug. The outcomes discovered that histopathological changes of heart, aorta and liver exposed to hydrogen peroxide and cholesterol revealed congested blood vessels with inflammation relevant cells in their lumen with necrosis of hepatic cells and inflammation relevant cells collected in sinusoids and inner surfaces of the blood vessels and infiltration of macrophages and lymphocytes in the liver moreover to the infiltration of mononuclear cells in the heart while in the aorta showed the vacuolation in the sub intimae and vacuolation and increase the thickness of intimate layer. Furthermore, inflammation relevant cells particularly infiltration around aorta. While therapy with almond extracts and Atorvastatin lead to valuable changes in therapy of damaging happened in the heart, aorta and liver induced with hyperlipidemia. In addition a dose of 1000 mg/kg of aqueous extracts of sweet almond was the best in treatment of hyperlipidemia.

Metalic foreign body in the liver of cow: a case report

O.A. Abdullah; H.Kh. Ismail

Iraqi Journal of Veterinary Sciences, Volume 28, Issue 2, Pages 109-111
DOI: 10.33899/ijvs.2014.117978

On necropsy of a two years old clinically healthy cow admitted to Mosul abattoir at postmortem inspection slaughtering establishment a metalic foreign body (as a piece of wire) was identified in the region of the liver. Gross examination revealed multiple abscess involving the liver, as well a large area of necrosis around foreign body penetration. Microscopically
Suppurative inflammation in addition to foreign body granulomatous reaction.