Author : Zabiba, Isam Mohammed Jaber

Morphometrical and histochemical foundation of pancreas and ductal system in white-eared bulbul (Pycnonotus leucotis)

Salim Salih Ali Al-Khakani; Isam Mohammed Jaber Zabiba; Kadthem Al-zubaidi; Ekhlas Al-alwany

Iraqi Journal of Veterinary Sciences, 2019, Volume 33, Issue 1, Pages 99-104
DOI: 10.33899/ijvs.2019.125521.1043

The present study was designed to find the macroscopic, microscopic and histocamical properties in pancreas of white-eared bulbul (Pycnonotus leucotis) and ductal system, ten healthy adult birds were transferred to the veterinary anatomy laboratory in Al-Qasim green university. Macroscopic study revealed that the pancreas was white in color, formed from two lobes, the ventral lobe navicular in shape while the dorsal lobe was very thin like triangular in appearance but longer than the ventral lobe. The two lobes were not occupy the space between the descending and ascending limbs of duodenum, the mean weight of birds and whole pancreas was (27.6±3.04), (0.07±0.022) gm respectively, the mean weight of dorsal and ventral lobes was (0.034±0.005), (0.036±0.0054) gm respectively and the mean length of dorsal and ventral lobe was (1.3±0.05), (0.88±0.03) cm respectively. The pancreas was a small organs in white-eared bulbul. The result of microscopic study that the pancreas in white-eared bulbul similar to other birds and covered by a thin C.T capsule with mesothelium cells. The pancreas parenchyma was consisted of exocrine and endocrine portions, the Langerhans island appeared in dorsal lobe in all histological sections which composed of different shapes and sizes. The intercalated ducts of ductal system lined by simple to low cuboidal cells then the epithelia changed to simple cuboidal in interlobular duct and become columnar in larger ducts. The main excretory ducts composed of three histological layers mucosa, muscularis and adventitia.

Renoprotection by Garcinia mangostana L. pericarp extract in streptozotocin-induced diabetic mice

Arif Nur Muhammad Ansori; Raden Joko Kuncoroningrat Kuncoroningrat Kuncoroningrat; Suhailah Hayaza; Dwi Winarni; Saikhu Akhmad Husen

Iraqi Journal of Veterinary Sciences, 2019, Volume 33, Issue 1, Pages 13-19
DOI: 10.33899/ijvs.2019.125513.1035

The purpose of this study was to evaluate the renoprotective effect of the Garcinia mangostana L. pericarp extract (GMPE) on plasma creatinine and renal proximal tubules of streptozotocin-induced diabetic mice. This study used 36 male Balb/c strain mice. The samples were divided into 6 groups, namely KN (normal control), KD (diabetic control), KM (metformin control), and P (treatment group) comprising: P1 (50 mg GMPE/kg body weight), P2 (100 mg GMPE/kg body weight), as well as P3 (200 mg GMPE/kg body weight). The GMPE and metformin suspension were administered orally for 14 days on the diabetic mice. The diabetes was induced by intraperitoneal injection of STZ multiple at low-dose of 30 mg/kg body weight daily for five consecutive days. On day 15, mice were terminated. Data of plasma creatinine and renal proximal tubule damage levels or the number of swelling and necrosis cells were analyzed. Interestingly and it showed that administration of GMPE could reduce the plasma creatinine level and the ameliorate renal proximal tubules of streptozotocin-induced diabetic mice. In conclusion, the renoprotective effect of GMPE in streptozotocin-induced diabetic mice was associated with the attenuation in oxidative stress and inflammatory, which also had antidiabetic and antioxidant activities.