Author : Al-Wataar, Barra

Creatine kinase and C reactive protein as an indicator for tissue damage in the retained placenta in cows

Barra D. Al-Watar; Eman Lazim; Osama H. Al-Hyani

Iraqi Journal of Veterinary Sciences, 2021, Volume 35, Issue 1, Pages 163-167
DOI: 10.33899/ijvs.2020.126496.1338

The current study aimed to investigate concentrations of Creatine Kinase (CK) and C Reactive Protein (CRP) in blood serum of cows with the retained placenta to compare with cows of normal parturition, also, to compare their concentrations in association with fetal sex, previous parturition and time to placenta expel. A total of sixty-three cows suffered from retained placenta with cows of normal parturition (n=10) were included in the current study during the period starting from December 2018 till September 2019. Blood samples (10 ml) were collected from the jugular vein to determine the concentration of CRP and CK in blood serum by enzyme-linked immunosorbent assay (ELIZA). The result showed that the serum concentrations of CRP and CK in cows suffering from retained placenta was 28.03 μg/ml and 238.93 ng/ml significantly higher than in cows with normal parturition 22.80 µg/ml and 137.50 ng/ml. The result of ELIZA showed that the serum concentration of CRP and CK in cows did not significantly affect depending upon the sex of the fetus and previous parturition history. On other hands, the serum concentration of CRP and CK in cows significantly differed depending upon the time to expel the placenta. In conclusion, the serum concentration of CRP and CK in cows with retained placenta was markedly higher than recorded in cows with normal parturition, and this can be used to identify days past since cows with retained placenta and to give a prognosis for their health and reproductive status.